Title

Dietary, evolutionary, and modernizing influences on the prevalence of type 2 diabetes

Authors

Authors

L. S. Lieberman

Comments

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Abbreviated Journal Title

Annu. Rev. Nutr.

Keywords

obesity; Westernized diets; Syndrome X; dietary globalization; thrifty; genotypes; NUTRITION EXAMINATION SURVEYS; GENETICALLY UNKNOWN FOODS; BODY-MASS; INDEX; INSULIN-RESISTANCE; THRIFTY GENOTYPE; BIRTH-WEIGHT; FETAL-GROWTH; SOCIOECONOMIC-STATUS; NATIONAL-HEALTH; LIFE-STYLE; Nutrition & Dietetics

Abstract

An evolutionary perspective is used to elucidate the etiology of the current epidemic of type 2 diabetes estimated at 151 million people. Our primate legacy, fossil hominid, and hunting-gathering lifestyles selected for adaptive metabolically thrifty genotypes and phenotypes are rendered deleterious through modem lifestyles that increase energy input and reduce output. The processes of modernization or globalization include the availability and abundance of calorically dense/low-fiber/high-glycemic foods and the adoption of sedentary Western lifestyles, leading to obesity among both children and adults in developed and developing countries. These trends are projected to continue for a number of decades.

Journal Title

Annual Review of Nutrition

Volume

23

Publication Date

1-1-2003

Document Type

Review

Language

English

First Page

345

Last Page

377

WOS Identifier

WOS:000185093400017

ISSN

0199-9885

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