Dietary, evolutionary, and modernizing influences on the prevalence of type 2 diabetes

    Authors

    L. S. Lieberman

    Comments

    Authors: contact us about adding a copy of your work at STARS@ucf.edu

    Abbreviated Journal Title

    Annu. Rev. Nutr.

    Keywords

    obesity; Westernized diets; Syndrome X; dietary globalization; thrifty; genotypes; NUTRITION EXAMINATION SURVEYS; GENETICALLY UNKNOWN FOODS; BODY-MASS; INDEX; INSULIN-RESISTANCE; THRIFTY GENOTYPE; BIRTH-WEIGHT; FETAL-GROWTH; SOCIOECONOMIC-STATUS; NATIONAL-HEALTH; LIFE-STYLE; Nutrition & Dietetics

    Abstract

    An evolutionary perspective is used to elucidate the etiology of the current epidemic of type 2 diabetes estimated at 151 million people. Our primate legacy, fossil hominid, and hunting-gathering lifestyles selected for adaptive metabolically thrifty genotypes and phenotypes are rendered deleterious through modem lifestyles that increase energy input and reduce output. The processes of modernization or globalization include the availability and abundance of calorically dense/low-fiber/high-glycemic foods and the adoption of sedentary Western lifestyles, leading to obesity among both children and adults in developed and developing countries. These trends are projected to continue for a number of decades.

    Journal Title

    Annual Review of Nutrition

    Volume

    23

    Publication Date

    1-1-2003

    Document Type

    Review

    Language

    English

    First Page

    345

    Last Page

    377

    WOS Identifier

    WOS:000185093400017

    ISSN

    0199-9885

    Share

    COinS