Title

The application of vinylogous iminium salt derivatives to an efficient relay synthesis of the pyrrole containing alkaloids polycitone A and B

Authors

Authors

J. T. Gupton; R. B. Miller; K. E. Krumpe; S. C. Clough; E. J. Banner; R. P. F. Kanters; K. X. Du; K. M. Keertikar; N. E. Lauerman; J. M. Solano; B. R. Adams; D. W. Callahan; B. A. Little; A. B. Scharf;J. A. Sikorski

Comments

Authors: contact us about adding a copy of your work at STARS@ucf.edu

Abbreviated Journal Title

Tetrahedron

Keywords

Chemistry, Organic

Abstract

A new and efficient relay synthesis of the marine natural products polycitone A and B is described. The new strategy relies on the formation of 2,4-disubstituted pyrroles from a vinamidinium salt followed by electrophilic substitution at the 5-position of the pyrrole and Suzuki coupling at the 4-position to produce the tetrasubstituted heterocycle efficiently and with complete control of regiochemistry. (C) 2004 Elsevier Ltd. All rights reserved.

Journal Title

Tetrahedron

Volume

61

Issue/Number

7

Publication Date

1-1-2005

Document Type

Article

DOI Link

http://dx.doi.org/10.1016/j.tet.2004.12.015

Language

English

First Page

1845

Last Page

1854

WOS Identifier

WOS:000226915200023

ISSN

0040-4020

Recommended Citation

"The application of vinylogous iminium salt derivatives to an efficient relay synthesis of the pyrrole containing alkaloids polycitone A and B" (2005). Faculty Bibliography 2000s. 5240.
https://stars.library.ucf.edu/facultybib2000/5240