Tree-augmented Cox proportional hazards models

Authors

    Authors

    X. G. Su;C. L. Tsai

    Comments

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    Abbreviated Journal Title

    Biostatistics

    Keywords

    BIC; censored survival times; Cox proportional hazards models; survival; trees; CORONARY HEART-DISEASE; STRUCTURED SURVIVAL ANALYSIS; WESTERN; COLLABORATIVE GROUP; FOLLOW-UP EXPERIENCE; REGRESSION; RESIDUALS; MORTALITY; GOODNESS; TESTS; Mathematical & Computational Biology; Statistics & Probability

    Abstract

    We study a hybrid model that combines Cox proportional hazards regression with tree-structured modeling. The main idea is to use step functions, provided by a tree structure, to 'augment' Cox (1972) proportional hazards models. The proposed model not only provides a natural assessment of the adequacy of the Cox proportional hazards model but also improves its model fitting without loss of interpretability. Both simulations and an empirical example are provided to illustrate the use of the proposed method.

    Journal Title

    Biostatistics

    Volume

    6

    Issue/Number

    3

    Publication Date

    1-1-2005

    Document Type

    Article

    Language

    English

    First Page

    486

    Last Page

    499

    WOS Identifier

    WOS:000230715600010

    ISSN

    1465-4644

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