Title

Vacancy engineered ceria nanostructures for protection from radiation-induced cellular damage

Authors

Authors

R. W. Tarnuzzer; J. Colon; S. Patil;S. Seal

Comments

Authors: contact us about adding a copy of your work at STARS@ucf.edu

Abbreviated Journal Title

Nano Lett.

Keywords

NANOCRYSTALLINE CERIA; NANO-PARTICLES; CELLS; Chemistry, Multidisciplinary; Chemistry, Physical; Nanoscience &; Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter

Abstract

The ability of engineered cerium oxide nanoparticles to confer radioprotection was examined. Human normal and tumor cells were treated with nanoceria and irradiated, and cell survival was measured. Treatment of normal cells conferred almost 99% protection from radiation-induced cell death, whereas the same concentration showed almost no protection of tumor cells. For the first time, nanoceria is shown to confer radioprotection to a normal human breast line but not to a human breast tumor line, MCF-7.

Journal Title

Nano Letters

Volume

5

Issue/Number

12

Publication Date

1-1-2005

Document Type

Article

Language

English

First Page

2573

Last Page

2577

WOS Identifier

WOS:000234357000044

ISSN

1530-6984

Share

COinS