Title

The potential toxicity of nanomaterials - The role of surfaces

Authors

Authors

A. S. Karakoti; L. L. Hench;S. Seal

Comments

Authors: contact us about adding a copy of your work at STARS@ucf.edu

Abbreviated Journal Title

Jom

Keywords

WALL CARBON NANOTUBES; ULTRAFINE PARTICLES; PULMONARY TOXICITY; AIR-POLLUTION; FIBROUS GLASS; NANOTOXICOLOGY; EXPOSURE; MODEL; MICE; SIZE; Materials Science, Multidisciplinary; Metallurgy & Metallurgical; Engineering; Mineralogy; Mining & Mineral Processing

Abstract

Nanotechnology has attracted considerable attention in the scientific community ever since its emergence as a powerful basic and applied science tool. While beneficial aspects of nanomaterials are well visioned, several reports have suggested the negative impact of nanomaterials on living cells. The diverse array of surface properties achieved due to reduction in particle size that catalyzes the surface chemistry of nanoparticles is responsible for their toxic potential. Physical parameters such as surface area, particle size, surface charge, and zeta potential are very important for providing mechanistic details in the uptake, persistence, and biological toxicity, of nanoparticles inside living cells. This short review provides insights into the physical, chemical, and interfacial parameters on the toxic potential of nanomaterials. While nanotechnology has promised invaluable progress in science and technology, the onus rests on the scientific community to predict the unknown outcome on the biological system for its safe proliferation.

Journal Title

Jom

Volume

58

Issue/Number

7

Publication Date

1-1-2006

Document Type

Article

Language

English

First Page

77

Last Page

82

WOS Identifier

WOS:000238927900016

ISSN

1047-4838

Share

COinS