Stability of virus nanoparticles on substrates under applied load with atomic force microscope

    Authors

    Y. Zhao; N. Mahajan; S. Long; Q. Wang;J. Fang

    Comments

    Authors: contact us about adding a copy of your work at STARS@ucf.edu

    Abbreviated Journal Title

    Micro Nano Lett.

    Keywords

    COWPEA MOSAIC-VIRUS; BUILDING-BLOCKS; PROTEIN CAGE; PARTICLES; NANOWIRES; SURFACES; DISPLAY; CAPSIDS; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary

    Abstract

    Virus nanoparticles are supramolecular structures containing a nucleic acid ( either DNA or RNA) core surrounded by a protein layer. In this article, we study the stability of cowpea mosaic virus (CPMV) nanoparticles on mica, Au and graphite surfaces under applied load by atomic force microscope in the tapping mode. The CPMV nanoparticles adsorbed on the hydrophilic mica and Au surfaces are intact, while on the hydrophobic graphite surface, the CPMV nanoparticles undergo the morphological changes from spherical to ellipsoidal and doughnut shapes with the increase in applied load. An understanding of the stability of the CPMV nanoparticles on substrates is critical in developing some of their applications in nanotechnology.

    Journal Title

    Micro & Nano Letters

    Volume

    1

    Issue/Number

    1

    Publication Date

    1-1-2006

    Document Type

    Article

    Language

    English

    First Page

    1

    Last Page

    4

    WOS Identifier

    WOS:000252698400001

    ISSN

    1750-0443

    Share

    COinS