High-fructose corn syrup, energy intake, and appetite regulation

    Authors

    K. J. Melanson; T. J. Angelopoulos; V. Nguyen; L. Zukley; J. Lowndes;J. M. Rippe

    Comments

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    Abstract

    High-fructose corn syrup (HFCS) has been implicated in excess weight gain through mechanisms seen in some acute feeding studies and by virtue of its abundance in the food supply during years of increasing obesity. Compared with pure glucose, fructose is thought to be associated with insufficient secretion of insulin and leptin and suppression of ghrelin. However, when HFCS is compared with sucrose, the more commonly consumed sweetener, such differences are not apparent, and appetite and energy intake do not differ in the short-term. Longer-term studies on connections between HFCS, potential mechanisms, and body weight have not been conducted. The main objective of this review was to examine collective data on associations between consumption of HFCS and energy balance, with particular focus on energy intake and its regulation. Am J Clin Nutr 2008; 88(suppl): 1738S-44S.

    Journal Title

    American Journal of Clinical Nutrition

    Volume

    88

    Issue/Number

    6

    Publication Date

    1-1-2008

    Document Type

    Article

    First Page

    1738S

    Last Page

    1744S

    WOS Identifier

    WOS:000261449200042

    ISSN

    0002-9165

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