Title

High-fructose corn syrup, energy intake, and appetite regulation

Authors

Authors

K. J. Melanson; T. J. Angelopoulos; V. Nguyen; L. Zukley; J. Lowndes;J. M. Rippe

Comments

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Abstract

High-fructose corn syrup (HFCS) has been implicated in excess weight gain through mechanisms seen in some acute feeding studies and by virtue of its abundance in the food supply during years of increasing obesity. Compared with pure glucose, fructose is thought to be associated with insufficient secretion of insulin and leptin and suppression of ghrelin. However, when HFCS is compared with sucrose, the more commonly consumed sweetener, such differences are not apparent, and appetite and energy intake do not differ in the short-term. Longer-term studies on connections between HFCS, potential mechanisms, and body weight have not been conducted. The main objective of this review was to examine collective data on associations between consumption of HFCS and energy balance, with particular focus on energy intake and its regulation. Am J Clin Nutr 2008; 88(suppl): 1738S-44S.

Journal Title

American Journal of Clinical Nutrition

Volume

88

Issue/Number

6

Publication Date

1-1-2008

Document Type

Article

First Page

1738S

Last Page

1744S

WOS Identifier

WOS:000261449200042

ISSN

0002-9165

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