Nanofibrous scaffold engineering using electrospinning

    Authors

    R. Murugan; Z. M. Huang; F. Yang;S. Ramakrishna

    Comments

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    Abbreviated Journal Title

    J. Nanosci. Nanotechnol.

    Keywords

    electrospinning; nanofibers; scaffolds; polymers; tissue engineering; BIODEGRADABLE POLYMER SCAFFOLDS; EXTRACELLULAR-MATRIX; TISSUE; ACID); COLLAGEN; BONE; CELL; NANOCOMPOSITES; FABRICATION; PROSPECTS; Chemistry, Multidisciplinary; Nanoscience & Nanotechnology; Materials; Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter

    Abstract

    Scaffold plays a critical role in tissue engineering where it provides necessary structural support for the cells to accommodate and to guide their growth in the three dimensional space into a specific tissue. Therefore, engineering scaffolds favorable for cell/tissue growth is of great importance and a pre-requisite for scaffold-based tissue engineering. Electrospinning is a versatile method that has been recently adapted in engineering nano-fibrous scaffolds that mimic the structural features of biological extracellular matrix (ECM). It offers many advantages over conventional scaffold methodologies, for example, capable of producing ultra-fine fibers with high porosity, high spatial orientation, high aspect ratio, and high surface area, which are highly required for the initial cell attachment, tissue formation, and continued function. Considering these astonishing merits, this article emphasis on nano-fibrous scaffold engineering by electrospinning.

    Journal Title

    Journal of Nanoscience and Nanotechnology

    Volume

    7

    Issue/Number

    12

    Publication Date

    1-1-2007

    Document Type

    Article; Proceedings Paper

    Language

    English

    First Page

    4595

    Last Page

    4603

    WOS Identifier

    WOS:000252511300054

    ISSN

    1533-4880

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