Title

Nanofibrous scaffold engineering using electrospinning

Authors

Authors

R. Murugan; Z. M. Huang; F. Yang;S. Ramakrishna

Comments

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Abbreviated Journal Title

J. Nanosci. Nanotechnol.

Keywords

electrospinning; nanofibers; scaffolds; polymers; tissue engineering; BIODEGRADABLE POLYMER SCAFFOLDS; EXTRACELLULAR-MATRIX; TISSUE; ACID); COLLAGEN; BONE; CELL; NANOCOMPOSITES; FABRICATION; PROSPECTS; Chemistry, Multidisciplinary; Nanoscience & Nanotechnology; Materials; Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter

Abstract

Scaffold plays a critical role in tissue engineering where it provides necessary structural support for the cells to accommodate and to guide their growth in the three dimensional space into a specific tissue. Therefore, engineering scaffolds favorable for cell/tissue growth is of great importance and a pre-requisite for scaffold-based tissue engineering. Electrospinning is a versatile method that has been recently adapted in engineering nano-fibrous scaffolds that mimic the structural features of biological extracellular matrix (ECM). It offers many advantages over conventional scaffold methodologies, for example, capable of producing ultra-fine fibers with high porosity, high spatial orientation, high aspect ratio, and high surface area, which are highly required for the initial cell attachment, tissue formation, and continued function. Considering these astonishing merits, this article emphasis on nano-fibrous scaffold engineering by electrospinning.

Journal Title

Journal of Nanoscience and Nanotechnology

Volume

7

Issue/Number

12

Publication Date

1-1-2007

Document Type

Article; Proceedings Paper

Language

English

First Page

4595

Last Page

4603

WOS Identifier

WOS:000252511300054

ISSN

1533-4880

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