Hemoglobin magnetism in aqueous solution probed by muon spin relaxation and future applications to brain research

    Authors

    K. Nagamine; K. Shimomura; H. Miyadera; Y. J. Kim; R. H. Scheicher; T. P. Das;J. S. Schultz

    Comments

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    Abbreviated Journal Title

    Proc. Jpn. Acad. Ser. B-Phys. Biol. Sci.

    Keywords

    muon; muon spin relaxation; hemoglobin; blood magnetism; oxygenation; OXYHEMOGLOBIN; BLOOD; Multidisciplinary Sciences

    Abstract

    A marked difference in spin relaxation behavior due to hemoglobin magnetism was found for positive unions ( +) in deoxyhemoglobin in comparison with that observed in oxyhemoglobin in aqueous solution at room temperature under zero and external longitudinal magnetic fields upto 0.4 Tesla. At the same time, small but significant unique relaxation pattern was observed in nonmagnetic oxyhemoglobin. Combined with our previous measurements on hemoglobin in human blood, application of this type of measurement to the studies of the level of oxygenation in various regions of the human brain is suggested.

    Journal Title

    Proceedings of the Japan Academy Series B-Physical and Biological Sciences

    Volume

    83

    Issue/Number

    4

    Publication Date

    1-1-2007

    Document Type

    Article

    Language

    English

    First Page

    120

    Last Page

    126

    WOS Identifier

    WOS:000247285500003

    ISSN

    0386-2208

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