Title

Accelerated multiple-pass moving average: A novel algorithm for baseline estimation in CE and its application to baseline correction on real-time bases

Authors

Authors

A. Solis; M. Rex; A. D. Campiglia;P. Sojo

Comments

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Abbreviated Journal Title

Electrophoresis

Keywords

accelerated multiple-pass moving average; CE; real-time baseline; correction; CAPILLARY-ELECTROPHORESIS; Biochemical Research Methods; Chemistry, Analytical

Abstract

We present a novel algorithm for baseline estimation in CE. The new algorithm which we have named as accelerated multiple-pass moving average (AMPMA) is combined to three preexisting low-pass filters, spike-removal, moving average, and multi-pass moving average filter, to achieve real-time baseline correction with commercial instrumentation. The successful performance of AMPMA is demonstrated with simulated and experimental data. Straightforward comparison of experimental data clearly shows the improvement AMPMA provides to the linear fitting, LOD, and accuracy (absolute error) of CE analysis.

Journal Title

Electrophoresis

Volume

28

Issue/Number

8

Publication Date

1-1-2007

Document Type

Article

Language

English

First Page

1181

Last Page

1188

WOS Identifier

WOS:000246116100003

ISSN

0173-0835

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