Title

A new water-soluble near-neutral ratiometric fluorescent pH indicator

Authors

Authors

S. Yao; K. J. Schafer-Hales;K. D. Belfield

Comments

Authors: contact us about adding a copy of your work at STARS@ucf.edu

Abbreviated Journal Title

Org. Lett.

Keywords

ABSORBING FLUORENE DERIVATIVES; ASCITES TUMOR-CELLS; SERIES; CHROMOPHORES; EXCITATION; PROBES; RANGE; Chemistry, Organic

Abstract

Donor-pi-acceptor fluorene derivative 1c is a near-neutral pH indicator whose pK(a) of similar to 7.0 was determined by both absorption and fluorescence methods. 1c satisfies important criteria for a sensitive ratiomeric fluorescent pH indicator with a distinctive isoemissive point, good dispersion in cell cytosol, and low cytotoxicity. Furthermore, its 2PA cross section of 100 GM in its neutral form suggests its. potential in two-photon fluorescence imaging applications.

Journal Title

Organic Letters

Volume

9

Issue/Number

26

Publication Date

1-1-2007

Document Type

Article

Language

English

First Page

5645

Last Page

5648

WOS Identifier

WOS:000251614900079

ISSN

1523-7060

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