Title

Reactive radical scavenging and xanthine oxidase inhibition of proanthocyanidins from Carallia brachiata

Authors

Authors

P. Phuwapraisirisan; P. Sowanthip; D. H. Miles;S. Tip-Pyang

Comments

Authors: contact us about adding a copy of your work at STARS@ucf.edu

Abbreviated Journal Title

Phytother. Res.

Keywords

Carallia brachiata; carallidin; antioxidant; proanthocyanidin; xanthine; oxidase; radical scavenging; CONSTITUENTS; FLAVONOIDS; Chemistry, Medicinal; Pharmacology & Pharmacy

Abstract

Antioxidant-guided separation of Carallia brachiata bark led to a new A-type trimeric proanthocyanidin named carallidin (1), along with mahuarmin A (2) and p-hydroxy benzoic acid (3). The structure of 1 was fully characterized by interpretation of spectroscopic data and chemical means. Compounds 1 and 2 exhibited radical scavenging against DPPH (IC50 102 and 182 mu m) and superoxide radical (IC50 1.47 and 9.74 mu m). In addition, 1 and 2 also inhibited xanthine oxidase with IC, values of 12.9 and 16.0 mu m. Copyright (c) 2006 John Wiley & Sons, Ltd.

Journal Title

Phytotherapy Research

Volume

20

Issue/Number

6

Publication Date

1-1-2006

Document Type

Article

DOI Link

http://dx.doi.org/10.1002/ptr.1877

Language

English

First Page

458

Last Page

461

WOS Identifier

WOS:000238370200006

ISSN

0951-418X

Recommended Citation

"Reactive radical scavenging and xanthine oxidase inhibition of proanthocyanidins from Carallia brachiata" (2006). Faculty Bibliography 2000s. 7888.
https://stars.library.ucf.edu/facultybib2000/7888