Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants

    Authors

    H. Daniell; S. J. Streatfield;K. Wycoff

    Comments

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    Abbreviated Journal Title

    Trends Plant Sci.

    Keywords

    TRANSGENIC TOBACCO PLANTS; MOUTH-DISEASE VIRUS; B SURFACE-ANTIGEN; MONOCLONAL-ANTIBODY; POTATO PLANTS; EXPRESSION; PROTEIN; IMMUNOGENICITY; MICE; IMMUNIZATION; Plant Sciences

    Abstract

    The use of plants for medicinal purposes dates back thousands of years but genetic engineering of plants to produce desired biopharmaceuticals is much more recent. As the demand for biopharmaceuticals is expected to increase, it would be wise to ensure that they will be available in significantly larger amounts, on a cost-effective basis. Currently, the cost of biopharmaceuticals limits their availability. Plant-derived biopharmaceuticals are cheap to produce and store, easy to scale up for mass production, and safer than those derived from animals. Here, we discuss recent developments in this field and possible environmental concerns.

    Journal Title

    Trends in Plant Science

    Volume

    6

    Issue/Number

    5

    Publication Date

    1-1-2001

    Document Type

    Review

    Language

    English

    First Page

    219

    Last Page

    226

    WOS Identifier

    WOS:000168576900011

    ISSN

    1360-1385

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