Title

Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants

Authors

Authors

H. Daniell; S. J. Streatfield;K. Wycoff

Comments

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Abbreviated Journal Title

Trends Plant Sci.

Keywords

TRANSGENIC TOBACCO PLANTS; MOUTH-DISEASE VIRUS; B SURFACE-ANTIGEN; MONOCLONAL-ANTIBODY; POTATO PLANTS; EXPRESSION; PROTEIN; IMMUNOGENICITY; MICE; IMMUNIZATION; Plant Sciences

Abstract

The use of plants for medicinal purposes dates back thousands of years but genetic engineering of plants to produce desired biopharmaceuticals is much more recent. As the demand for biopharmaceuticals is expected to increase, it would be wise to ensure that they will be available in significantly larger amounts, on a cost-effective basis. Currently, the cost of biopharmaceuticals limits their availability. Plant-derived biopharmaceuticals are cheap to produce and store, easy to scale up for mass production, and safer than those derived from animals. Here, we discuss recent developments in this field and possible environmental concerns.

Journal Title

Trends in Plant Science

Volume

6

Issue/Number

5

Publication Date

1-1-2001

Document Type

Review

Language

English

First Page

219

Last Page

226

WOS Identifier

WOS:000168576900011

ISSN

1360-1385

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