Title

A Stoichiometric Model of the Kinetics of Nanoparticle Clusterings Mediated by Antigen-Antibody Interactions

Authors

Authors

J. P. Brennan;T. Chen

Comments

Authors: contact us about adding a copy of your work at STARS@ucf.edu

Abbreviated Journal Title

J. Comput. Theor. Nanosci.

Keywords

Immunoassay; Mass-Action Kinetic Model; Nanoparticles; Stoichiometry; DYNAMIC LIGHT-SCATTERING; INDUCED PARTICULATE AGGREGATION; AVERAGE; MOLECULAR-WEIGHTS; THEORETICAL-ANALYSIS; COMPLEXES; PROBES; IMMUNOASSAY; SENSORS; ASSAY; Chemistry, Multidisciplinary; Nanoscience & Nanotechnology; Materials; Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter

Abstract

Mass action models have been used to model chemical reactions. We use the methods of stoichiometry to model the formation of nanoparticle clusterings where the bond between the nanoparticles is formed by antibody-antigen-antibody interaction. The growth of such configurations can be determined and the change of the mean nanoparticle size determined. This model can be used to determine the concentration of antigen in solution.

Journal Title

Journal of Computational and Theoretical Nanoscience

Volume

8

Issue/Number

9

Publication Date

1-1-2011

Document Type

Article

Language

English

First Page

1653

Last Page

1658

WOS Identifier

WOS:000298514100004

ISSN

1546-1955

Share

COinS