Title

Osteogenesis imperfecta in the archeological record: An example from the Dakhleh Oasis, Egypt

Authors

Authors

D. J. Cope;T. L. Dupras

Comments

Authors: contact us about adding a copy of your work at STARS@ucf.edu

Abbreviated Journal Title

Int. J. Paleopathol.

Keywords

Osteogenesis imperfecta; Fetal skeletal remains; Paleopathology; Differential diagnosis; Egypt; Dakhleh Oasis; Paleontology; Pathology

Abstract

The present study evaluates a fetal skeleton (B532) from the Romano-Byzantine period Kellis 2 cemetery (circa A.D. 50-A.D. 450), in the Dakhleh Oasis, Egypt. This skeleton displays abnormal skeletal characteristics consisting of severe bowing of the long bones. Differential diagnoses using macroscopic and radiographic analyses indicate that this individual's pathological condition was caused by osteogenesis imperfecta (IO), possibly Type IIB/III, or Type IV OI, corroborating with characteristics reported in the clinical literature. Due to the severe bowing of the long bones, traditional aging methods could not be used for this individual. Baysian estimates of age indicate this individual was a fetus of approximately 38 weeks gestation. Although this condition has been diagnosed previously in the archeological literature, this burial represents the youngest aged example of osteogenesis imperfecta reported to date. (C) 2012 Elsevier Inc. All rights reserved.

Journal Title

International Journal of Paleopathology

Volume

1

Issue/Number

3-4

Publication Date

1-1-2011

Document Type

Article

Language

English

First Page

188

Last Page

199

WOS Identifier

WOS:000209142500011

ISSN

1879-9817

Share

COinS