Osteogenesis imperfecta in the archeological record: An example from the Dakhleh Oasis, Egypt

    Authors

    D. J. Cope;T. L. Dupras

    Comments

    Authors: contact us about adding a copy of your work at STARS@ucf.edu

    Abbreviated Journal Title

    Int. J. Paleopathol.

    Keywords

    Osteogenesis imperfecta; Fetal skeletal remains; Paleopathology; Differential diagnosis; Egypt; Dakhleh Oasis; Paleontology; Pathology

    Abstract

    The present study evaluates a fetal skeleton (B532) from the Romano-Byzantine period Kellis 2 cemetery (circa A.D. 50-A.D. 450), in the Dakhleh Oasis, Egypt. This skeleton displays abnormal skeletal characteristics consisting of severe bowing of the long bones. Differential diagnoses using macroscopic and radiographic analyses indicate that this individual's pathological condition was caused by osteogenesis imperfecta (IO), possibly Type IIB/III, or Type IV OI, corroborating with characteristics reported in the clinical literature. Due to the severe bowing of the long bones, traditional aging methods could not be used for this individual. Baysian estimates of age indicate this individual was a fetus of approximately 38 weeks gestation. Although this condition has been diagnosed previously in the archeological literature, this burial represents the youngest aged example of osteogenesis imperfecta reported to date. (C) 2012 Elsevier Inc. All rights reserved.

    Journal Title

    International Journal of Paleopathology

    Volume

    1

    Issue/Number

    3-4

    Publication Date

    1-1-2011

    Document Type

    Article

    Language

    English

    First Page

    188

    Last Page

    199

    WOS Identifier

    WOS:000209142500011

    ISSN

    1879-9817

    Share

    COinS