Title

Enzyme-assisted binary probe for sensitive detection of RNA and DNA

Authors

Authors

Y. V. Gerasimova; S. Peck;D. M. Kolpashchikov

Comments

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Abbreviated Journal Title

Chem. Commun.

Keywords

NUCLEIC-ACID ANALYSIS; MOLECULAR BEACONS; HYBRIDIZATION; DEOXYRIBOZYME; TARGET; HII; Chemistry, Multidisciplinary

Abstract

The new enzyme-assisted assay for DNA/RNA detection provides real-time fluorescent signal readout along with low limit of detection and high discrimination power toward a single-base substitution. Requiring only two new unmodified DNA oligonucleotides for the detection of each new analyte, the assay is an efficient tool for low-cost analysis of multiple analytes.

Journal Title

Chemical Communications

Volume

46

Issue/Number

46

Publication Date

1-1-2010

Document Type

Article

Language

English

First Page

8761

Last Page

8763

WOS Identifier

WOS:000284229400017

ISSN

1359-7345

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