Enzyme-assisted binary probe for sensitive detection of RNA and DNA

    Authors

    Y. V. Gerasimova; S. Peck;D. M. Kolpashchikov

    Comments

    Authors: contact us about adding a copy of your work at [email protected]

    Abbreviated Journal Title

    Chem. Commun.

    Keywords

    NUCLEIC-ACID ANALYSIS; MOLECULAR BEACONS; HYBRIDIZATION; DEOXYRIBOZYME; TARGET; HII; Chemistry, Multidisciplinary

    Abstract

    The new enzyme-assisted assay for DNA/RNA detection provides real-time fluorescent signal readout along with low limit of detection and high discrimination power toward a single-base substitution. Requiring only two new unmodified DNA oligonucleotides for the detection of each new analyte, the assay is an efficient tool for low-cost analysis of multiple analytes.

    Journal Title

    Chemical Communications

    Volume

    46

    Issue/Number

    46

    Publication Date

    1-1-2010

    Document Type

    Article

    Language

    English

    First Page

    8761

    Last Page

    8763

    WOS Identifier

    WOS:000284229400017

    ISSN

    1359-7345

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