Gold nanoparticles deposited capillaries for in-capillary microextraction capillary zone electrophoresis of monohydroxy-polycyclic aromatic hydrocarbons

    Authors

    H. Y. Wang; G. Knobel; W. B. Wilson; K. Calimag-Williams;A. D. Campiglia

    Comments

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    Abbreviated Journal Title

    Electrophoresis

    Keywords

    Capillary zone electrophoresis; Gold nanoparticles; In-capillary; microextraction; Monohydroxy metabolites; Polycyclic aromatic; hydrocarbons; SOLID-PHASE EXTRACTION; PERFORMANCE LIQUID-CHROMATOGRAPHY; INDUCED; FLUORESCENCE DETECTION; DRINKING-WATER SAMPLES; HIGH-SENSITIVITY CELL; TEE-SPLIT INTERFACE; MASS-SPECTROMETRY; SPE-CE; BIOLOGICAL SAMPLES; FLOW-INJECTION; Biochemical Research Methods; Chemistry, Analytical

    Abstract

    This article presents the first application of gold nanoparticles deposited capillaries as pre-concentration devices for in-capillary microextraction CZE and their use for the analysis of monohydroxy-polycyclic aromatic hydrocarbons in synthetic urine samples. The successful separation of 1-hydroxypyrene, 9-hydroxyphenanthrene, 3-hydroxybenzo[a] pyrene (3-OHbap), 4-hydroxybenzo[a] pyrene and 5-hydroxybenzo[a] pyrene under a single set of electrophoretic conditions is demonstrated as well as the feasibility to obtain competitive ultraviolet absorption LOD with commercial instrumentation. Enrichment factors ranging from 87 (9-OHphe) to 100 (3-OHbap) made it possible to obtain LOD ranging from 9 ng/mL (9-OHphe and 3-OHbap) to 14 ng/mL (4-hydroxybenzo[a] pyrene).

    Journal Title

    Electrophoresis

    Volume

    32

    Issue/Number

    6-7

    Publication Date

    1-1-2011

    Document Type

    Article

    Language

    English

    First Page

    720

    Last Page

    727

    WOS Identifier

    WOS:000288602000011

    ISSN

    0173-0835

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