Cerium oxide nanoparticles scavenge nitric oxide radical ((NO)-N-center dot)

    Authors

    J. M. Dowding; T. Dosani; A. Kumar; S. Seal;W. T. Self

    Comments

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    Abbreviated Journal Title

    Chem. Commun.

    Keywords

    NO; COMPLEXES; MODEL; HEMOGLOBIN; MECHANISMS; DISEASE; HEALTH; Chemistry, Multidisciplinary

    Abstract

    In this study we have obtained evidence that cerium oxide nanoparticles (CeO2 NPs) are able to scavenge nitric oxide radical. Surprisingly, this activity is present in CeO2 NPs with a lower level of cerium in the 3+ state (CeO2 NPs with low 3+/4+ ratio and therefore a reduced number of oxygen vacancies), in contrast to the superoxide scavenging properties which are correlated with an increased level of cerium in the 3+ state (CeO2 NPs with high 3+/4+ ratio and therefore an increased number of oxygen vacancies).

    Journal Title

    Chemical Communications

    Volume

    48

    Issue/Number

    40

    Publication Date

    1-1-2012

    Document Type

    Article

    Language

    English

    First Page

    4896

    Last Page

    4898

    WOS Identifier

    WOS:000303125600032

    ISSN

    1359-7345

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