Biocompatibility and Conductometric Property of Sol-Gel Derived ZnO/PVP Nanocomposite Biosensor Film

    Authors

    O. J. Ilegbusi; H. W. Song;R. Chakrabarti

    Comments

    Authors: contact us about adding a copy of your work at STARS@ucf.edu

    Abbreviated Journal Title

    J. Bionic Eng.

    Keywords

    zinc oxide film; biosensor; nanocomposite film; sol-gel; ZINC-OXIDE FILMS; GROWTH-INHIBITION; VAPOR-DEPOSITION; ZNO; OXIDATION; BACTERIA; POWDERS; Engineering, Multidisciplinary; Materials Science, Biomaterials; Robotics

    Abstract

    Nanocrystalline ZnO and ZnO/PVP nanocomposite films have been prepared by the sol-gel dip-coating technique from zinc acetate precursor on silicon wafer and Pyrex glass substrates. The films were characterized using atomic force microscopy for morphology, and X-ray photoelectron spectroscopy and Fourier transform infrared spectroscopy for chemical analysis. Thermally untreated and annealed films were studied in order to analyze the influence of temperature on the formation and properties of the films. The films have a uniform void-free surface and the grain size increases with the annealing temperature. The cell viability assays indicate that the growth rate of BPH cells incubated in the presence of ZnO was significantly reduced (35% of the control) compared to that of untreated controls, indicating antibacterial activity of ZnO as a result of the generation of hydrogen peroxide. The sensor characteristic of ZnO/PVP nanocomposite was also demonstrated by measuring the change in conductivity Upon exposure to superoxide anion radical..

    Journal Title

    Journal of Bionic Engineering

    Volume

    7

    Publication Date

    1-1-2010

    Document Type

    Article; Proceedings Paper

    Language

    English

    First Page

    S30

    Last Page

    S35

    WOS Identifier

    WOS:000282392000005

    ISSN

    1672-6529

    Share

    COinS