Abbreviated Journal Title
Am. J. Transl. Res.
Keywords
Kruppel-like factor 8 (KLF8); cancer; FOCAL ADHESION KINASE; CELL-CYCLE PROGRESSION; KLF8 TRANSCRIPTION; IN-VIVO; IDENTIFICATION; GENE; ACTIVATION; EXPRESSION; INVASION; FINGERS; Oncology; Medicine, Research & Experimental
Abstract
Kruppel-like factor 8 (KLF8) is a young member of the KLF transcription factor family proteins. It is highly overexpressed in several types of human cancers and regulates various cellular processes important for tumor progression. Increasing evidence has made KLF8 a new focus in cancer research and a potential target for cancer therapy. This review highlights the role of KLF8 in cancer by summarizing the up-to-date studies into its structure, function as a dual transcription factor, target genes and mechanisms of expression and modifications.
Journal Title
American Journal of Translational Research
Volume
4
Issue/Number
3
Publication Date
1-1-2012
Document Type
Review
Language
English
First Page
357
Last Page
363
WOS Identifier
ISSN
1943-8141
Recommended Citation
Lahiri, Satadru K. and Zhao, Jihe, "Kruppel-like factor 8 emerges as an important regulator of cancer" (2012). Faculty Bibliography 2010s. 2899.
https://stars.library.ucf.edu/facultybib2010/2899
Comments
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