Title

Current Status of Salvage Robot-Assisted Laparoscopic Prostatectomy for Radiorecurrent Prostate Cancer

Authors

Authors

B. Rocco; G. Cozzi; M. G. Spinelli; A. Grasso; D. Varisco; R. F. Coelho;V. R. Patel

Comments

Authors: contact us about adding a copy of your work at STARS@ucf.edu

Abbreviated Journal Title

Curr. Urol. Rep.

Keywords

Prostate cancer; Surgery; Endourology; Radiorecurrent prostate cancer; Recurrence; Radiation therapy; Radiation failure; Brachytherapy; Salvage; robot-assisted laparoscopic prostatectomy; sRALP; Urology & Nephrology

Abstract

Radiation therapy (RT) is one of the treatment options for prostate cancer (PCa). Transperineal low-dose rate brachytherapy (BT) is another safe and effective technique for low-risk PCa. Recurrence after RT for localized PCa can be defined by a PSA value of 2 ng/mL above the nadir after RT, and biochemical recurrence (BCR) rate after RT is 40-60 %. In case of radiorecurrent PCa, treatment options include salvage radical prostatectomy (RP), cryotherapy, high-intensity focused ultrasound (HIFU), and salvage BT. Only salvage RP has cancer control results for over 10-year follow-up in a substantial portion of patients (30-40 %). However, salvage RP is technically demanding, and experienced surgeons are needed; in fact, RT-induced cystitis, fibrosis, and tissue plane obliteration can lead to significant complications, such as rectal injuries, anastomotic stricture, and urinary incontinence. This review describes indications, oncologic and functional outcomes, surgical techniques, and complications of salvage robot-assisted RP.

Journal Title

Current Urology Reports

Volume

13

Issue/Number

3

Publication Date

1-1-2012

Document Type

Article

Language

English

First Page

195

Last Page

201

WOS Identifier

WOS:000208943500003

ISSN

1527-2737

Share

COinS