Current Status of Salvage Robot-Assisted Laparoscopic Prostatectomy for Radiorecurrent Prostate Cancer

    Authors

    B. Rocco; G. Cozzi; M. G. Spinelli; A. Grasso; D. Varisco; R. F. Coelho;V. R. Patel

    Comments

    Authors: contact us about adding a copy of your work at STARS@ucf.edu

    Abbreviated Journal Title

    Curr. Urol. Rep.

    Keywords

    Prostate cancer; Surgery; Endourology; Radiorecurrent prostate cancer; Recurrence; Radiation therapy; Radiation failure; Brachytherapy; Salvage; robot-assisted laparoscopic prostatectomy; sRALP; Urology & Nephrology

    Abstract

    Radiation therapy (RT) is one of the treatment options for prostate cancer (PCa). Transperineal low-dose rate brachytherapy (BT) is another safe and effective technique for low-risk PCa. Recurrence after RT for localized PCa can be defined by a PSA value of 2 ng/mL above the nadir after RT, and biochemical recurrence (BCR) rate after RT is 40-60 %. In case of radiorecurrent PCa, treatment options include salvage radical prostatectomy (RP), cryotherapy, high-intensity focused ultrasound (HIFU), and salvage BT. Only salvage RP has cancer control results for over 10-year follow-up in a substantial portion of patients (30-40 %). However, salvage RP is technically demanding, and experienced surgeons are needed; in fact, RT-induced cystitis, fibrosis, and tissue plane obliteration can lead to significant complications, such as rectal injuries, anastomotic stricture, and urinary incontinence. This review describes indications, oncologic and functional outcomes, surgical techniques, and complications of salvage robot-assisted RP.

    Journal Title

    Current Urology Reports

    Volume

    13

    Issue/Number

    3

    Publication Date

    1-1-2012

    Document Type

    Article

    Language

    English

    First Page

    195

    Last Page

    201

    WOS Identifier

    WOS:000208943500003

    ISSN

    1527-2737

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