Title

The Metabolic and Endocrine Response and Health Implications of Consuming Sugar-Sweetened Beverages: Findings From Recent Randomized Controlled Trials

Authors

Authors

J. M. Rippe

Comments

Authors: contact us about adding a copy of your work at STARS@ucf.edu

Abbreviated Journal Title

Adv. Nutr.

Keywords

FRUCTOSE CORN SYRUP; CONTROLLED FEEDING TRIALS; AMERICAN-HEART-ASSOCIATION; NORMAL DIETARY CONSUMPTION; FATTY; LIVER-DISEASE; DE-NOVO LIPOGENESIS; BODY-WEIGHT; INSULIN SENSITIVITY; BLOOD-PRESSURE; NONNUTRITIVE SWEETENERS; Nutrition & Dietetics

Abstract

Fructose-containing sugars, including fructose itself, high fructose corn syrup (HFCS), and sucrose have engendered considerable controversy. The effects of HFCS and sucrose in sugar-sweetened beverages, in particular, have generated intense scientific debate that has spilled over to the public. This controversy is related to well-known differences in metabolism between fructose and glucose in the liver. In addition, research studies have often been conducted comparing pure fructose and pure glucose even though neither is consumed to any appreciable degree in isolation in the human diet. Other evidence has been drawn from animal studies and epidemiologic or cohort studies. Few randomized controlled trials (RCTs) have compared HFCS with sucrose (the 2 sugars most commonly consumed in the human diet) at dosage amounts within the normal human consumption range. This review compares results of recently concluded RCTs with other forms of evidence related to fructose, HFCS, and sucrose. We conclude that great caution must be used when suggesting adverse health effects of consuming these sugars in the normal way they are consumed and at the normal amounts in the human diet, because RCTs do not support adverse health consequences at these doses when employing these sugars.

Journal Title

Advances in Nutrition

Volume

4

Issue/Number

6

Publication Date

1-1-2013

Document Type

Article; Proceedings Paper

Language

English

First Page

677

Last Page

686

WOS Identifier

WOS:000327112900011

ISSN

2161-8313

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