Polarization dependent two-photon absorption spectroscopy on a naturally occurring biomarker (curcumin) in solution: A theoretical-experimental study

    Authors

    J. A. Tiburcio-Moreno; J. J. Alvarado-Gil; C. Diaz; L. Echevarria;F. E. Hernandez

    Comments

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    Abbreviated Journal Title

    Chem. Phys. Lett.

    Keywords

    CIRCULAR-LINEAR DICHROISM; IN-VIVO; MOUSE MODEL; DENSITY; CHROMOPHORES; MOLECULES; EXCHANGE; PLAQUES; STORAGE; CELLS; Chemistry, Physical; Physics, Atomic, Molecular & Chemical

    Abstract

    We report on the theoretical-experimental analysis of the two-photon absorption (TPA) and two-photon circular-linear dichroism (TPCLD) spectra of (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione (curcumin) in Tetrahydrofuran (THF) solution. The measurement of the full TPA spectrum of this molecule reveals a maximum TPA cross-section at 740 nm, i.e. more than 10 times larger than the maximum reported in the literature at 800 nm for the application of curcumin in bioimaging. The TPCLD spectrum exposes the symmetry of the main excited-states involved in the two-photon excitation process. TD-DFT calculations support the experimental results. These outcomes are expected to expand the application of natural-occurring dyes in bioimaging. (C) 2013 Elsevier B.V. All rights reserved.

    Journal Title

    Chemical Physics Letters

    Volume

    583

    Publication Date

    1-1-2013

    Document Type

    Article

    Language

    English

    First Page

    160

    Last Page

    164

    WOS Identifier

    WOS:000324304600031

    ISSN

    0009-2614

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