Title

Hydrogel-based capillary flow pumping in a hydrophobic microfluidic channel

Authors

Authors

Y. M. Bae; K. H. Lee; J. Yang; D. Heo;H. J. Cho

Comments

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Abbreviated Journal Title

Jpn. J. Appl. Phys.

Keywords

CYCLIC OLEFIN COPOLYMER; THERMOPLASTIC POLYMERS; IMMOBILIZATION; MICROCHANNEL; IMMUNOASSAY; FABRICATION; ANTIBODY; SYSTEMS; DEVICES; CHIPS; Physics, Applied

Abstract

In this study, we propose a novel method to generate a capillary pressure-driven flow in a microchannel with a hydrophobic surface. The microfluidic device has a wide channel in which a hydrogel pillar array is embedded. The hydrogel pillar array was formed in the microchannel by a photopolymerization process. The flow rate due to a capillary action was strongly dependent on the distance between the pillars. Moreover, our capillary pumping with a hydrogel pillar array sustained the flow for more than 5 min with a limited sample volume. Our microfluidic device provides two advantages: (1) the modification of the polymer surface to make it hydrophilic is not required and (2) the conventional polymer molding technique can be applied to produce microfluidic devices, instead of the precision molding technique. The results indicate the possible fabrication of various microfluidic chip devices that can be easily implemented in point-of-care diagnostics. (C) 2014 The Japan Society of Applied Physics

Journal Title

Japanese Journal of Applied Physics

Volume

53

Issue/Number

6

Publication Date

1-1-2014

Document Type

Article

Language

English

First Page

5

WOS Identifier

WOS:000338104600055

ISSN

0021-4922

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