Title
Therapeutic potential of nanoceria in regenerative medicine
Abbreviated Journal Title
MRS Bull.
Keywords
CERIUM OXIDE NANOPARTICLES; OXIDATIVE STRESS; CEO2 NANOPARTICLES; NEURONAL SURVIVAL; CELLS; RADIATION; PROTECT; MICE; NANOSTRUCTURES; PROLIFERATION; Materials Science, Multidisciplinary; Physics, Applied
Abstract
Tissue engineering and regenerative medicine aim to achieve functional restoration of tissue or cells damaged through disease, aging, or trauma. Advancement of tissue engineering requires innovation in the field of three-dimensional scaffolding and functionalization with bioactive molecules. Nanotechnology offers advanced materials with patterned nano-morphologies for cell growth and different molecular substrates that can support cell survival and functions. Cerium oxide nanoparticles (nanoceria) can control intracellular as well as extracellular reactive oxygen and nitrogen species. Recent findings suggest that nanoceria can enhance long-term cell survival, enable cell migration and proliferation, and promote stem cell differentiation. Moreover, the self-regenerative property of nanoceria permits a small dose to remain catalytically active for an extended time. This review summarizes the possibilities and applications of nanoceria in the field of tissue engineering and regenerative medicine.
Journal Title
Mrs Bulletin
Volume
39
Issue/Number
11
Publication Date
1-1-2014
Document Type
Article
Language
English
First Page
976
Last Page
983
WOS Identifier
ISSN
0883-7694
Recommended Citation
"Therapeutic potential of nanoceria in regenerative medicine" (2014). Faculty Bibliography 2010s. 5229.
https://stars.library.ucf.edu/facultybib2010/5229
Comments
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