Title

Nucleic Acid-Based Assays for the Detection of High-Risk Human Papillomavirus: A Technical Review

Authors

Authors

J. S. Gibson

Comments

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Abbreviated Journal Title

Cancer Cytopathol.

Keywords

human papillomavirus; molecular tests; HPV nucleic acid testing; cervical cancer; THINPREP SPECIMENS; CERVICAL-CANCER; HPV; MANAGEMENT; TESTS; PERFORMANCE; GUIDELINES; Oncology; Pathology

Abstract

Nucleic acid-based high-risk human papillomavirus (hrHPV) testing is essential to contemporary cervical cancer screening. The numbers of commercially available assays approved by the US Food and Drug Administration for HPV nucleic acid detection have increased, each offering various approaches to analysis. An understanding of the methodologies associated with HPV testing is important to the practice of laboratory medicine. An overview of instruments, chemistries, laboratory workflows, and test limitations associated with current US Food and Drug Administration-approved assays is provided. (C) 2014 American Cancer Society.

Journal Title

Cancer Cytopathology

Volume

122

Issue/Number

9

Publication Date

1-1-2014

Document Type

Review

Language

English

First Page

639

Last Page

645

WOS Identifier

WOS:000342340300003

ISSN

1934-662X

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