Title
Mediators of Monocyte Migration in Response to Recovery Modalities following Resistance Exercise
Abbreviated Journal Title
Mediat. Inflamm.
Keywords
INDUCED MUSCLE DAMAGE; ECCENTRIC EXERCISE; STRENUOUS EXERCISE; MAXIMAL; EXERCISE; EXPRESSION; HUMANS; STIMULATION; LEUKOCYTES; INFLAMMATION; CHEMOKINES; Cell Biology; Immunology
Abstract
Mediators of monocyte migration, complement receptor-3 (CR3), and chemokine ligand-4 (CCL4) were measured in response to recovery modalities following resistance exercise. Thirty resistance-trained men (23.1 +/- 2.9 y; 175.2 +/- 7.1 cm; 82.1 +/- 8.4 kg) were given neuromuscular electric stimulation (NMES), cold water immersion (CWI), or control (CON) treatments immediately following resistance exercise. Blood samples were obtained preexercise (PRE), immediately (IP), 30 minutes (30 P), 24 hours (24 H), and 48 hours (48 H) after exercise for measurement of circulating CCL4 and CR3 expression on CD14+ monocytes, by assay and flow cytometry. Circulating CCL4 showed no consistent changes. Inferential analysis indicated that CR3 expression was likely greater in CON at 30 P than NMES (90.0%) or CWI (86.8%). NMES was likely lower than CON at 24H (92.9%) and very likely lower at 48H (98.7%). Expression of CR3 following CWI was very likely greater than CON (96.5%) at 24H. The proportion of CR3+ monocytes was likely greater following CWI than NMES (85.8%) or CON (85.2%) at 24 H. The change in proportion of CR3+ monocytes was likely (86.4%) greater following NMES than CON from IP to 30 P. The increased expression of CR3 and increased proportion of CR3+ monocytes following CWI at 24 H indicate a potentially improved ability for monocyte adhesion to the endothelium, possibly improving phagocytosis of damaged tissues.
Journal Title
Mediators of Inflammation
Publication Date
1-1-2014
Document Type
Article
Language
English
First Page
9
WOS Identifier
ISSN
0962-9351
Recommended Citation
Jajtner, Adam R.; Fragala, Maren S.; Townsend, Jeremy R.; Gonzalez, Adam M.; Wells, Adam J.; Fukuda, David H.; Stout, Jeffrey R.; and Hoffman, Jay R., "Mediators of Monocyte Migration in Response to Recovery Modalities following Resistance Exercise" (2014). Faculty Bibliography 2010s. 5504.
https://stars.library.ucf.edu/facultybib2010/5504
Comments
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