beta-Hydroxy-beta-methylbutyrate (HMB) supplementation and resistance exercise significantly reduce abdominal adiposity in healthy elderly men

    Authors

    J. R. Stout; D. H. Fukuda; K. L. Kendall; A. E. Smith-Ryan; J. R. Moon;J. R. Hoffman

    Comments

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    Abbreviated Journal Title

    Exp. Gerontol.

    Keywords

    Aging; Abdominal fat mass; Exercise; beta-Hydroxy-beta-methylbutyrate; X-RAY ABSORPTIOMETRY; INSULIN SENSITIVITY; RELIABILITY; ADULTS; FAT; Geriatrics & Gerontology

    Abstract

    The effects of 12-weeks of HMB ingestion and resistance training (RT) on abdominal adiposity were examined in 48 men (66-78 yrs). All participants were randomly assigned to 1 of 4 groups: no-training placebo (NT-PL), HMB only (NT-HMB), RT with PL (RT-PL), or HMB with RT (RT-HMB). DXA was used to estimate abdominal fat mass (AFM) by placing the region of interest over the L1-L4 region of the spine. Outcomes were assessed by ANCOVA, with Bonferroni-corrected pairwise comparisons. Baseline AFM values were used as the covariate. The ANCOVA indicated a significant difference (p = 0.013) between group means for the adjusted posttest AFM values (mean (kg) +/- SE: NT-PL = 2.59 +/- 0.06; NT-HMB = 2.59 +/- 0.61; RT-PL = 2.59 +/- 0.62; RT-HMB = 2.34 +/- 0.61). The pairwise comparisons indicated that AFM following the intervention period in the RT-HMB group was significantly less than NT-PL (p = 0.013), NT-HMB (p = 0.011), and RT-PL (p = 0.010). These data suggested that HMB in combination with 12 weeks of RT decreased AFM in elderly men. (C) 2015 Elsevier Inc. All rights reserved.

    Journal Title

    Experimental Gerontology

    Volume

    64

    Publication Date

    1-1-2015

    Document Type

    Article

    Language

    English

    First Page

    33

    Last Page

    34

    WOS Identifier

    WOS:000350812800004

    ISSN

    0531-5565

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