Understanding the toxicity of aggregated zero valent copper nanoparticles against Escherichia coli

    Authors

    F. Rispoli; A. Angelov; D. Badia; A. Kumar; S. Seal;V. Shah

    Comments

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    Abbreviated Journal Title

    J. Hazard. Mater.

    Keywords

    Copper nanoparticles; Antibacterial activity; E. coli; Toxicity; Centroid design; IN-VIVO; NANOTOXICITY; PARTICLES; SILVER; Engineering, Environmental; Engineering, Civil; Environmental Sciences

    Abstract

    Copper nanoparticles are used in wide variety of applications and in the current study we report the antimicrobial activity of these particles. Influence of pH, temperature, aeration rate, concentration of nanoparticles and concentration of bacteria on the toxicity of copper nanoparticles against Escherichia coli have been studied using a centroid mixture design of experiment. The linear and quadratic regression model shows that the toxicity of copper nanoparticles not only depends on the primary effect of the parameters tested (pH, temperature, aeration, concentration of E. coli and concentration of nanoparticles), but also on the interactive effect of these parameters. (C) 2010 Elsevier B.V. All rights reserved.

    Journal Title

    Journal of Hazardous Materials

    Volume

    180

    Issue/Number

    1-3

    Publication Date

    1-1-2010

    Document Type

    Article

    Language

    English

    First Page

    212

    Last Page

    216

    WOS Identifier

    WOS:000279459600025

    ISSN

    0304-3894

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