High Impact Practices Student Showcase Spring 2026
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Course Code
HSC
Course Number
4930
Faculty/Instructor
Steven Burroughs
Faculty/Instructor Email
Steven.Burroughs@ucf.edu
Abstract, Summary, or Creative Statement
This group project was developed for the Health Sciences Seminar course. The purpose of this project was to analyze a clinical trial which evaluated the effectiveness of azithromycin in preventing pregnancy-related maternal sepsis or death. Azithromycin is a commonly prescribed, broad-spectrum oral antibiotic that is inexpensive and widely accessible; It has antibacterial and anti-inflammatory properties and may help prevent infection when used prophylactically. The study’s primary measurable outcomes were instances of maternal and neonatal death or sepsis within 6 weeks (42 days) postpartum. Based on the results, azithromycin was effective in preventing instances of sepsis maternally, but not within neonates. We believe that the intervention is inexpensive, safe, and easy to add to current labor and delivery practices. However, prospective research targeting neonatal populations is recommended to further evaluate effective sepsis prevention measures.
Keywords
Sepsis;Pregnancy;Antibiotics;Maternal Death Prevention
Recommended Citation
Martinez, Emily; Questel, Roldine; Baldwin, Willow; and Coffman, Emma, "Analysis of Azithromycin-Prevention in Labor Use Study" (2026). High Impact Practices Student Showcase Spring 2026. 93.
https://stars.library.ucf.edu/hip-2026spring/93
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