Abstract

Disclosed herein are compositions comprising a drug combination that comprises ZD and S3I-201, Das and S3I-201, ZD and AG490, or Das and AG490. The disclosed drug combinations target two or more functional elements such as EGFR or Src and Stat3 or Jaks in pancreatic cancer cells. Also disclosed herein are methods of using the disclosed compositions to cytotoxically affect pancreatic cancer cells and methods of making the disclosed compositions.

Document Type

Patent

Patent Number

US 8,685,941

Application Serial Number

13/131,840

Issue Date

4-1-2014

Current Assignee

UCFRF

Assignee at Issuance

UCFRF

College

Burnett School of Biomedical Sciences

Department

Biomolecular Science Center

Allowance Date

11-12-2013

Filing Date

5-27-2011

Assignee at Filing

UCFRF

Filing Type

National Filing Record

Donated

no

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