Abstract

In the present work, we report the development of two reverse transcription-quantitative polymerase chain reacton (RT-qPCR) assays for the definitve identification of newborn individuals. The methodology is based upon gene expresiion profiling analysis in which specific age groups are identified by detecting the relative quantity of expression of appropriate mRNA species. RNA is isolated from dried bloodstains is analyzed using the two duplex real-time PCR reactions for two variant novel forms of newborn specific gamma hemoglobin.

Document Type

Patent

Patent Number

US 7,276,340

Application Serial Number

11/232,313

Issue Date

10-2-2007

Current Assignee

UCFRF

Assignee at Issuance

UCFRF

College

College of Sciences

Department

National Center for Forensic Science

Allowance Date

6-14-2007

Filing Date

9-21-2005

Assignee at Filing

UCFRF

Filing Type

Nonprovisional Application Record

Donated

no

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