Abstract
The invention provides a composition comprising a plurality of nanoceria particles, a sufficient amount of at least one inhibitor of human carbonic anhydrase II associated with said plurality of nanoceria particles, and a pharmaceutically acceptable carrier containing said plurality of nanoceria particles with associated inhibitor. One preferred inhibitor of human carbonic anhydrase II comprises 4-carboxybenzene sulfonamide. The disclosed composition is useful in treatment of glaucoma.
Document Type
Patent
Patent Number
US 8,337,898 B2
Application Serial Number
13/154,849
Issue Date
12-25-2012
Current Assignee
Joint Assignment w/UCFRF: NDSU Research Foundation, Inc.
Assignee at Issuance
Joint Assignment w/UCFRF: NDSU Research Foundation, Inc.
College
Advanced Materials Processing & Analysis Center (AMPAC)
Department
Advanced Materials Processing & Analysis Center (AMPAC)
Allowance Date
8-20-2012
Filing Date
6-7-2011
Assignee at Filing
Joint Assignment w/UCFRF: NDSU Research Foundation, Inc.
Filing Type
Nonprovisional Application Record
Donated
no
Recommended Citation
Seal, Sudipta; Haldar, Manas; Mallik, Sanku; and Patil, Swanand, "Functionalized Nanoceria Composition for Ophthalmic Treatment DIV" (2012). UCF Patents. 203.
https://stars.library.ucf.edu/patents/203