Abstract

A class of proteins useful as inhibitors of prostasin and method for identifying them are provided. These proteins have the structure wherein the amino acids P1-P4 from the scissile bond are respectively leu-ile-ala-arg and the amino acids at positions P5-P15 are serpin sequences.

Document Type

Patent

Patent Number

US 7,666,981

Application Serial Number

10/434,349

Issue Date

2-23-2010

Current Assignee

UCFRF

Assignee at Issuance

UCFRF

College

Burnett School of Biomedical Sciences

Department

Molecular Biology & Microbiology

Allowance Date

8-27-2009

Filing Date

5-8-2003

Assignee at Filing

UCFRF

Filing Type

Nonprovisional Application Record

Donated

no

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