Abstract

Products and methods are provided for the restoring the endogenous expression of theta-defensins, such as retrocyclin-1, in mamallian cells. The present invention also includes products and methods for inhibiting sexually transmitted virus entry, e.g., HIV-1 virus entry, into a mammalian cell via, for example, administering to a subject an amount of a read-through mediating agent sufficient to induce exogenous expression of an amount of retrocyclin nonapeptides in the mammalian cell.

Document Type

Patent

Patent Number

US 8,765,698 B2

Application Serial Number

12/699,389

Issue Date

7-1-2014

Current Assignee

UCFRF

Assignee at Issuance

UCFRF

College

Burnett School of Biomedical Sciences

Department

Molecular Biology & Microbiology

Allowance Date

8-19-2013

Filing Date

2-3-2010

Assignee at Filing

UCFRF

Filing Type

Nonprovisional Application Record

Donated

no

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