Abstract

We propose a method of expanding stem cells and dedifferentiating cells by cultruing cells with cell cultrue extracts of embryonic stem cellas and or extracts from a regenerating limb. We demonstrated that co cultureing human bone marrow mesenchymal stem cells with sections of a lizard tail or mouse embryonic stem cells increases the stemness of the Msc. This allows for the creation of a cell cultruing system containing expgenous factors that facilitate increased expression of stem cells genes and dedifferentiation.

Document Type

Patent

Patent Number

US 8,105,832

Application Serial Number

12/176,647

Issue Date

1-31-2012

Current Assignee

UCFRF

Assignee at Issuance

UCFRF

College

Burnett School of Biomedical Sciences

Department

Biomolecular Science Center

Allowance Date

9-20-2011

Filing Date

7-21-2008

Assignee at Filing

UCFRF

Filing Type

Nonprovisional Application Record

Donated

no

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