Blood coagulation, Hemostasis
Two groups of New Zealand white rabbits were injected with homogenates from Tumorous-head (Tuh) and Wild-type (WT) Drosophila melanogaster. A third group was used as a saline injected control. Blood collected in both acute and chronic studies was subjected to various hematological and post mortem studies. The Tuh injected group showed a five-fold increase in thrombocytes (blood platelets) over the controls and four-fold increase over the wild-type group. Reduced clotting times were noted from acute to chronic studies in both tumorous and wild-type studies; however, the magnitude of change between the two groups was insignificant. Investigations involving electrophoretic banding patterns, differential blood cell counts, and comparative hematocrits, provided less significant results. The author concludes that the reduced clotting times reported in tumorous-head injected rabbits represent a decrease in bleeding time. This was caused by the more effective plugging of the damaged vessel by the increased number of platelets.
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Washington, David W.
Master of Science (M.S.)
College of Natural Sciences
Length of Campus-only Access
Masters Thesis (Open Access)
Blood -- Coagulation, Hemostasis
Cox, Alfred B., "Differential Clotting Responses of Rabbits to Injections of Homogenates from Wild-Type and Tumorous-Head Drosophila Melanogaster" (1978). Retrospective Theses and Dissertations. 282.