Title

Solid State Ultraviolet Laser (213 Nm) Ablation Of The Cornea And Synthetic Collagen Lenticules

Keywords

collagen; excimer lasers; non‐linear optical crystals; refractive surgery

Abstract

We used a Q‐switched Nd:YAG laser with non‐linear optical crystals to produce the 5th (213 nm) and the 4th (266 nm) harmonic frequencies. Using these two wavelengths, we ablated fresh porcine corneas and type I collagen synthetic epikeratoplasty lenticules. For the 213‐nm ablation, radiant exposure was 1.3 J/cm2. The ablation rate was 0.23 μm per pulse for the epikeratoplasty lenticules. We examined all tissues with light microscopy, transmission electron microscopy, and scanning electron microscopy. Histology for the 213‐nm ablation showed a clean ablation crater with minimal collagen lamellae disruption and a damage zone less than 1μm. In comparison, the 266 nm radiation showed more charring at the edges with a damage zone approximately 25 μm deep with disruption of the stromal lamella. Our results show that this solid state UV laser is a potential alternative to the excimer laser for cornea surgery. Copyright © 1991 Wiley‐Liss, Inc., A Wiley Company

Publication Date

1-1-1991

Publication Title

Lasers in Surgery and Medicine

Volume

11

Issue

6

Number of Pages

556-562

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1002/lsm.1900110610

Socpus ID

0025838260 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/0025838260

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