Title
Application Of 2-Substituted Vinamidinium Salts To The Synthesis Of 2,4-Disubstituted Pyrroles
Abstract
A variety of 2-substituted vinamidinium salts react with a-amino acid esters under basic conditions to produce 2-carbethoxy-4-substituted-pyrroles in good yield. The overall process represents a short and efficient synthesis of highly functionalized pyrroles from a-substituted acetic acid precursors. Such reactions may involve the intermediacy of azomethine ylids or “pentadienyl like” anions. © 1990, American Chemical Society. All rights reserved.
Publication Date
1-1-1990
Publication Title
Journal of Organic Chemistry
Volume
55
Issue
15
Number of Pages
4735-4740
Document Type
Article
Personal Identifier
scopus
DOI Link
https://doi.org/10.1021/jo00302a047
Copyright Status
Unknown
Socpus ID
0000586381 (Scopus)
Source API URL
https://api.elsevier.com/content/abstract/scopus_id/0000586381
STARS Citation
Gupton, John T.; Krolikowski, Dale A.; and Yu, Richard H., "Application Of 2-Substituted Vinamidinium Salts To The Synthesis Of 2,4-Disubstituted Pyrroles" (1990). Scopus Export 1990s. 1685.
https://stars.library.ucf.edu/scopus1990/1685