Title

The Application Of Vinylogous Iminium Salts And Related Synthons To The Regiocontrolled Preparation Of 2,3- And 2,5-Disubstituted Pyrroles

Abstract

The reaction of 1-substituted vinamidinium salts with sarcosine ethyl ester produced 2,3-disubstituted pyrroles; a similar reaction with glycine ethyl ester gave 2,5-disubstituted pyrroles. Reactions of related three-carbon synthons with sarcosine and glycine were studied under basic, neutral and acidic conditions which demonstrated the utility of these derivatives for the regiocontrolled preparation of disubstituted pyrroles.

Publication Date

5-13-1996

Publication Title

Tetrahedron

Volume

52

Issue

20

Number of Pages

6879-6892

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1016/0040-4020(96)00338-9

Socpus ID

0029873091 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/0029873091

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