Title
An Improved Synthesis of O-Benzoyl Protected Hydroxamates
Abstract
Several primary amines (R-NH2) were converted to their corresponding O-benzoyl protected hydroxamates under biphasic conditions. The intermediate (benzoyloxy)amines (R-NHOCOPh) were generated using benzoyl peroxide dissolved in CH2Cl2 and an aqueous carbonate buffer (pH 10.5) at room temperature. Subsequent acylation with R'COCl gave the protected hydroxamates (R'CONROCOPh) in good overall yields (56-89%).
Publication Date
1-1-1997
Publication Title
Journal of Organic Chemistry
Volume
62
Issue
23
Number of Pages
8104-8108
Document Type
Article
Personal Identifier
scopus
DOI Link
https://doi.org/10.1021/jo971126q
Copyright Status
Unknown
Socpus ID
0008970533 (Scopus)
Source API URL
https://api.elsevier.com/content/abstract/scopus_id/0008970533
STARS Citation
Wang, Queenie Xianghong; King, Jennifer; and Phanstiel IV, Otto, "An Improved Synthesis of O-Benzoyl Protected Hydroxamates" (1997). Scopus Export 1990s. 2919.
https://stars.library.ucf.edu/scopus1990/2919