Title

The application of disubstituted vinylogous iminium salts and related synthons to the regiocontrolled preparation of unsymmetrical 2,3,4- trisubstituted pyrroles

Keywords

Chloroenals; Pyrroles; Vinylogous amides; Vinylogous iminium salts

Abstract

Reactions of 2,3-disubstituted chloropropeniminium salts and related synthons with ethyl glycinate, ethyl N-methylglycinate, and ethyl N- benzylglycinate have been studied under acidic, basic and neutral conditions. Such reactions have resulted in efficient and selective methodology for the synthesis of unsymmetrical 2,3,4-trisubstituted pyrrole systems.

Publication Date

5-14-1998

Publication Title

Tetrahedron

Volume

54

Issue

20

Number of Pages

5075-5088

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1016/S0040-4020(98)00247-6

Socpus ID

0032516285 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/0032516285

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