Title
An Efficient, Regiocontrolled Synthesis Of 5-Aryl-2-Carbethoxypyrroles From 3-Aryl-3-Chloropropeniminium Salts
Abstract
A variety of 3-aryl-3-chloropropeniminium salts react with α-amino acid esters under basic conditions to produce 2-carbethoxy-5-arylpyrroles in a regioselective manner. The overall process represents a short, efficient, and convergent synthesis of 2,5-disubstituted pyrroles, and azomethine ylides or azapentadienyl anions may be involved as intermediates. © 1992, American Chemical Society. All rights reserved.
Publication Date
9-1-1992
Publication Title
Journal of Organic Chemistry
Volume
57
Issue
20
Number of Pages
5480-5483
Document Type
Article
Identifier
scopus
Personal Identifier
scopus
DOI Link
https://doi.org/10.1021/jo00046a033
Copyright Status
Unknown
Socpus ID
0001440625 (Scopus)
Source API URL
https://api.elsevier.com/content/abstract/scopus_id/0001440625
STARS Citation
Gupton, John T.; Krolikowski, Dale A.; and Yu, Richard H., "An Efficient, Regiocontrolled Synthesis Of 5-Aryl-2-Carbethoxypyrroles From 3-Aryl-3-Chloropropeniminium Salts" (1992). Scopus Export 1990s. 906.
https://stars.library.ucf.edu/scopus1990/906