Title
Nanoscale Mechanics Of Solid-Supported Multilayered Lipid Films By Force Measurement
Keywords
Atomic force microscopy (AFM); Bilayer membrane; Lipid films; Nanomechanics; Solution spreading; Spin-coating; Structure and elastic properties; Young's modulus
Abstract
Using atomic force microscopy and molecular force probe, we have studied the structure and nanomechanical response to nano-indentation of multilayered films of dioleoylphosphatidylcholine films prepared by solution spreading, spin-coating, and capillary methods. The influence of the film thickness on the apparent elastic (Young's) modulus is investigated. Young's moduli of samples prepared by the different methods were found to be similar for sufficiently thick films. An ostensible influence of substrate coupling on the apparent Young's modulus is observed for thinner lipid films. The results are discussed in comparison with previously reported estimates for supported lipid bilayers (membranes) and cells. © 2008 Elsevier B.V. All rights reserved.
Publication Date
6-2-2008
Publication Title
Thin Solid Films
Volume
516
Issue
15
Number of Pages
5039-5045
Document Type
Article
Personal Identifier
scopus
DOI Link
https://doi.org/10.1016/j.tsf.2008.02.023
Copyright Status
Unknown
Socpus ID
42649108046 (Scopus)
Source API URL
https://api.elsevier.com/content/abstract/scopus_id/42649108046
STARS Citation
Ngwa, Wilfred; Chen, Kezheng; Sahgal, Alok; Stepanov, Eugene V.; and Luo, Weili, "Nanoscale Mechanics Of Solid-Supported Multilayered Lipid Films By Force Measurement" (2008). Scopus Export 2000s. 10003.
https://stars.library.ucf.edu/scopus2000/10003