Title

A New Water-Soluble Near-Neutral Ratiometric Fluorescent Ph Indicator

Abstract

Donor-π-acceptor fluorene derivative 1 is a near-neutral pH indicator whose pKa of ~7.0 was determined by both absorption and fluorescence methods. 1 satisfies important criteria for a sensitive ratiomeric fluorescent pH indicator with a distinctive isoemissive point, good dispersion in cell cytosol, and low cytotoxicity. Furthermore, its 2PA cross-section of 100 GM in its neutral form suggests its potential in two-photon fluorescence imaging applications. © 2008 Optical Society of America.

Publication Date

1-1-2008

Publication Title

Biomedical Optics, BIOMED 2008

Number of Pages

-

Document Type

Article; Proceedings Paper

Personal Identifier

scopus

DOI Link

https://doi.org/10.1364/biomed.2008.bsue90

Socpus ID

84884305087 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/84884305087

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