Title

Dietary, Evolutionary, And Modernizing Influences On The Prevalence Of Type 2 Diabetes

Keywords

Dietary globalization; Obesity; Syndrome X; Thrifty genotypes; Westernized diets

Abstract

An evolutionary perspective is used to elucidate the etiology of the current epidemic of type 2 diabetes estimated at 151 million people. Our primate legacy, fossil hominid, and hunting-gathering lifestyles selected for adaptive metabolically thrifty genotypes and phenotypes are rendered deleterious through modern lifestyles that increase energy input and reduce output. The processes of modernization or globalization include the availability and abundance of calorically dense/low-fiber/highglycemic foods and the adoption of sedentary Western lifestyles, leading to obesity among both children and adults in developed and developing countries. These trends are projected to continue for a number of decades.

Publication Date

9-11-2003

Publication Title

Annual Review of Nutrition

Volume

23

Number of Pages

345-377

Document Type

Review

Personal Identifier

scopus

DOI Link

https://doi.org/10.1146/annurev.nutr.23.011702.073212

Socpus ID

0041363358 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/0041363358

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