Title

Multigene Engineering: Dawn Of An Exciting New Era In Biotechnology

Abstract

Development of a rice variety enriched in provitamin A, the accumulation of polyhydroxybutyrate polyester in Arabidopsis nuclear transgenic plants (with enzymes targeted to chloroplasts in both), and the expression of bacterial operons via the chloroplast genome are recent landmark achievements in multigene engineering. Hyper-expression of transgenes has resulted in the formation of insecticidal protein crystals or inclusion bodies of pharmaceutical proteins in transgenic chloroplasts, achieving the highest level of transgene expression ever reported in transgenic plants. These achievements illustrate the potential of multigene engineering to realize benefits of the post-genomic revolution.

Publication Date

4-1-2002

Publication Title

Current Opinion in Biotechnology

Volume

13

Issue

2

Number of Pages

136-141

Document Type

Review

Personal Identifier

scopus

DOI Link

https://doi.org/10.1016/S0958-1669(02)00297-5

Socpus ID

0036535792 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/0036535792

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