Title
The Application Of Vinylogous Iminium Salt Derivatives To An Efficient Relay Synthesis Of The Pyrrole Containing Alkaloids Polycitone A And B
Keywords
Marine natural product; Pyrrole; Vinamidinium salt
Abstract
A new and efficient relay synthesis of the marine natural products polycitone A and B is described. The new strategy relies on the formation of 2,4-disubstituted pyrroles from a vinamidinium salt followed by electrophilic substitution at the 5-position of the pyrrole and Suzuki coupling at the 4-position to produce the tetrasubstituted heterocycle efficiently and with complete control of regiochemistry. © 2004 Elsevier Ltd. All rights reserved.
Publication Date
2-14-2005
Publication Title
Tetrahedron
Volume
61
Issue
7
Number of Pages
1845-1854
Document Type
Article
Personal Identifier
scopus
DOI Link
https://doi.org/10.1016/j.tet.2004.12.015
Copyright Status
Unknown
Socpus ID
19944434175 (Scopus)
Source API URL
https://api.elsevier.com/content/abstract/scopus_id/19944434175
STARS Citation
Gupton, John T.; Miller, Robert B.; and Krumpe, Keith E., "The Application Of Vinylogous Iminium Salt Derivatives To An Efficient Relay Synthesis Of The Pyrrole Containing Alkaloids Polycitone A And B" (2005). Scopus Export 2000s. 4104.
https://stars.library.ucf.edu/scopus2000/4104