Title

A New Water-Soluble Near-Neutral Ratiometric Fluorescent Ph Indicator

Abstract

Donor-π-acceptor fluorene derivative 1c is a near-neutral pH indicator whose pKa of ∼7.0 was determined by both absorption and fluorescence methods. 1c satisfies important criteria for a sensitive ratiomeric fluorescent pH indicator with a distinctive isoemissive point, good dispersion in cell cytosol, and low cytotoxicity. Furthermore, its 2PA cross section of 100 GM in its neutral form suggests its potential in two-photon fluorescence imaging applications. © 2007 American Chemical Society.

Publication Date

12-20-2007

Publication Title

Organic Letters

Volume

9

Issue

26

Number of Pages

5645-5648

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1021/ol7026366

Socpus ID

38349161691 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/38349161691

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