Title

Integration Of Functional Myotubes With A Bio-Mems Device For Non-Invasive Interrogation

Abstract

We have developed a biological micro-electromechanical system (Bio-MEMS) device consisting of surface-modified microfabricated silicon cantilevers and an AFM detection apparatus for the study of cultured myotubes. With this system we are able to selectively stimulate the myotubes as well as report on a variety of physiological properties of the myotubes in real time and in a high-throughput manner. This system will serve as the foundation for future work integrating multiple tissue types for the creation of Bio-MEMS analogues of complex tissues and biological circuits. © The Royal Society of Chemistry.

Publication Date

1-1-2007

Publication Title

Lab on a Chip

Volume

7

Issue

7

Number of Pages

920-922

Document Type

Article

Personal Identifier

scopus

DOI Link

https://doi.org/10.1039/b617939h

Socpus ID

34347211410 (Scopus)

Source API URL

https://api.elsevier.com/content/abstract/scopus_id/34347211410

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